Oxygenation of unsaturated fatty acids by the vesicular gland of sheep
M Hamberg, B Samuelsson - Journal of Biological Chemistry, 1967 - ASBMB
The products formed on oxygenation of certain unsaturated fatty acids in preparations of
sheep vesicular gland have been studied. Oxygenation of linoleic acid yielded 9-hydroxy-
10, 12-octadecadienoic acid (82%) and 13-hydroxy-9, 11-octadecadienoic acid (18%).
Oxygenation of 8, 11, 14-eicosatrienoic acid yielded 11-hydroxy-8, 12, 14-eicosatrienoic
acid, 15-hydroxy-8, 11, 13-eicosatrienoic acid, 12-hydroxy-8, 10-heptadecadienoic acid,
prostaglandin E 1 (PGE 1), and prostaglandin F 1α. The biosynthesis of 12-hydroxy-8, 10 …
sheep vesicular gland have been studied. Oxygenation of linoleic acid yielded 9-hydroxy-
10, 12-octadecadienoic acid (82%) and 13-hydroxy-9, 11-octadecadienoic acid (18%).
Oxygenation of 8, 11, 14-eicosatrienoic acid yielded 11-hydroxy-8, 12, 14-eicosatrienoic
acid, 15-hydroxy-8, 11, 13-eicosatrienoic acid, 12-hydroxy-8, 10-heptadecadienoic acid,
prostaglandin E 1 (PGE 1), and prostaglandin F 1α. The biosynthesis of 12-hydroxy-8, 10 …