Enhancing the efficacy of engraftment of cord blood for hematopoietic cell transplantation
HE Broxmeyer - Transfusion and Apheresis Science, 2016 - Elsevier
Clinical cord blood (CB) hematopoietic cell transplantation (HCT) has progressed well since
the initial successful CB HCT that saved the life of a young boy with Fanconi anemia. The
recipient is alive and well now 28 years out since that first transplant with CB cells from his
HLA-matched sister. CB HCT has now been used to treat over 35,000 patients with various
malignant and non-malignant disorders mainly using HLA-matched or partially HLA-
disparate allogeneic CB cells. There are advantages and disadvantages to using CB for …
the initial successful CB HCT that saved the life of a young boy with Fanconi anemia. The
recipient is alive and well now 28 years out since that first transplant with CB cells from his
HLA-matched sister. CB HCT has now been used to treat over 35,000 patients with various
malignant and non-malignant disorders mainly using HLA-matched or partially HLA-
disparate allogeneic CB cells. There are advantages and disadvantages to using CB for …