IgE is a type of antibody linked with host defense against parasitic infection. However, in
most countries with a low incidence of parasitic infection, high IgE is more commonly
associated with disorders of immune dysregulation, such as atopy. There are various
pulmonary conditions associated with high serum IgE. IgE is one of the drivers of asthma
associated with atopy, which led to the development of omalizumab, an anti-IgE monoclonal
antibody, as an asthma therapy. 1 High serum IgE is associated with allergic …