Preferential expression of MUC6 in oncocytic and pancreatobiliary types of intraductal papillary neoplasms highlights a pyloropancreatic pathway, distinct from the …
O Basturk, S Khayyata, DS Klimstra… - The American journal …, 2010 - journals.lww.com
The expression of different MUC glycoproteins has helped define cellular lineage in variety
of pancreatic neoplasms, and has helped identify distinct carcinogenic pathways such as the
intestinal pathway characterized by diffuse/strong MUC2/CDX2 expression in intestinal-type
intraductal papillary mucinous neoplasms (IPMNs) and their associated colloid carcinomas
(CCs). In this study, the expression profile of MUC6, a pyloric-type mucin, was investigated
in both preinvasive and invasive pancreatic neoplasia. Florid papillary (“in-situ”) …
of pancreatic neoplasms, and has helped identify distinct carcinogenic pathways such as the
intestinal pathway characterized by diffuse/strong MUC2/CDX2 expression in intestinal-type
intraductal papillary mucinous neoplasms (IPMNs) and their associated colloid carcinomas
(CCs). In this study, the expression profile of MUC6, a pyloric-type mucin, was investigated
in both preinvasive and invasive pancreatic neoplasia. Florid papillary (“in-situ”) …