Abdominal aortic aneurysm (AAA) is an inflammatory disease associated with macrophage
accumulation in the adventitia, oxidative stress, medial elastin degradation and aortic
dilation. Progression of AAA is linked to increased risk of rupture, which carries a high
mortality rate. Drug therapies trialled to date lack efficacy and although aneurysm repair is
available for patients with large aneurysm, peri-surgical morbidity and mortality have been
widely reported. Recent studies using rodent models of AAA suggest that long chain omega …