Gestational exercise protects adult male offspring from high-fat diet-induced hepatic steatosis
Background & Aims Mounting evidence indicates that maternal exercise confers protection
to adult offspring against various diseases. Here we hypothesized that maternal exercise
during gestation would reduce high-fat diet (HFD)-induced hepatic steatosis in adult rat
offspring. Methods Following conception, pregnant dams were divided into either voluntary
wheel running exercise (GE) or wheel-locked sedentary (GS) groups throughout gestation
(days 4–21). Post-weaning, offspring received either normal chow diet (CD; 10% fat, 70 …
to adult offspring against various diseases. Here we hypothesized that maternal exercise
during gestation would reduce high-fat diet (HFD)-induced hepatic steatosis in adult rat
offspring. Methods Following conception, pregnant dams were divided into either voluntary
wheel running exercise (GE) or wheel-locked sedentary (GS) groups throughout gestation
(days 4–21). Post-weaning, offspring received either normal chow diet (CD; 10% fat, 70 …