[HTML][HTML] Weight trajectories through infancy and childhood and risk of non-alcoholic fatty liver disease in adolescence: the ALSPAC study

EL Anderson, LD Howe, A Fraser, MP Callaway… - Journal of …, 2014 - Elsevier
Background & Aims Adiposity is a key risk factor for NAFLD. Few studies have examined
prospective associations of infant and childhood adiposity with subsequent NAFLD risk. We
examined associations of weight-for-height trajectories from birth to age 10 with liver
outcomes in adolescence, and assessed the extent to which associations are mediated
through fat mass at the time of outcome assessment. Methods Individual trajectories of
weight and height were estimated for participants in the Avon Longitudinal Study of Parents …