BDNF and GDNF expression in discrete populations of nociceptors
C Salio, F Ferrini - Annals of Anatomy-Anatomischer Anzeiger, 2016 - Elsevier
The brain derived neurotrophic factor (BDNF) and the glial cell line-derived neurotrophic
factor (GDNF) are growth factors that promote the survival and differentiation of sensory
neurons and intervene in the control of nociceptive neurotransmission. Both are synthesized
by dorsal root ganglion (DRG) neurons and are anterogradely transported to the central
terminals of the spinal cord dorsal horn. To better investigate the specific expression pattern
of BDNF and GDNF in nociceptors, we studied their localization in relationship to other …
factor (GDNF) are growth factors that promote the survival and differentiation of sensory
neurons and intervene in the control of nociceptive neurotransmission. Both are synthesized
by dorsal root ganglion (DRG) neurons and are anterogradely transported to the central
terminals of the spinal cord dorsal horn. To better investigate the specific expression pattern
of BDNF and GDNF in nociceptors, we studied their localization in relationship to other …