Impact of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccinations on reported pertussis cases among those 11 to 18 years of age in an era of …

TH Skoff, SW Martin - JAMA pediatrics, 2016 - jamanetwork.com
Importance There is accumulating literature on waning acellular pertussis vaccine–induced
immunity, confirming the results of studies assessing the duration of protection of pertussis
vaccines. Objective To evaluate the tetanus toxoid, reduced diphtheria toxoid, and acellular
pertussis (Tdap) vaccine's effect over time among those 11 to 18 years old, while accounting
for the transition from whole-cell to acellular pertussis vaccines for the childhood primary
series. Design, Setting, and Participants Extended, retrospective analysis of reported …