Association of V617F Jak2 mutation with the risk of thrombosis among patients with essential thrombocythaemia or idiopathic myelofibrosis: a systematic review
F Lussana, S Caberlon, C Pagani, PW Kamphuisen… - Thrombosis research, 2009 - Elsevier
INTRODUCTION: Many studies evaluated the association of V617F Jak-2 with the risk of
thrombosis in patients with essential thrombocythaemia, but the results of these studies were
inconsistent. Few studies evaluated the association of V617F Jak-2 mutation with the risk of
thrombosis in patients with idiopathic myelofibrosis. Therefore, we performed a systematic
review of the studies that assessed the risk of thrombosis associated with V617F Jak-2 in
patients with ET or IM. MATERIALS AND METHODS: We searched MEDLINE and EMBASE …
thrombosis in patients with essential thrombocythaemia, but the results of these studies were
inconsistent. Few studies evaluated the association of V617F Jak-2 mutation with the risk of
thrombosis in patients with idiopathic myelofibrosis. Therefore, we performed a systematic
review of the studies that assessed the risk of thrombosis associated with V617F Jak-2 in
patients with ET or IM. MATERIALS AND METHODS: We searched MEDLINE and EMBASE …