p38 Mitogen-activated protein kinase activation and cell localization in human glomerulonephritis: correlation with renal injury
C Stambe, DJ Nikolic-Paterson, PA Hill… - Journal of the …, 2004 - journals.lww.com
Activation of the p38 mitogen-activated protein kinase (MAPK) signal transduction pathway
plays an important role in the inflammatory response. It was postulated that p38 MAPK is
important in the pathogenesis of human glomerulonephritis and contributes to the
development of renal injury. p38 MAPK activation was examined by immunodetection for
dual phosphorylated p38 (p-p38) in normal human kidney and 77 renal biopsy specimens
encompassing a wide spectrum of glomerulonephritides. In normal kidney, p-p38 …
plays an important role in the inflammatory response. It was postulated that p38 MAPK is
important in the pathogenesis of human glomerulonephritis and contributes to the
development of renal injury. p38 MAPK activation was examined by immunodetection for
dual phosphorylated p38 (p-p38) in normal human kidney and 77 renal biopsy specimens
encompassing a wide spectrum of glomerulonephritides. In normal kidney, p-p38 …