Overview and findings from the religious orders study
DA Bennett, JA Schneider… - Current Alzheimer …, 2012 - ingentaconnect.com
DA Bennett, JA Schneider, Z Arvanitakis, RS Wilson
Current Alzheimer Research, 2012•ingentaconnect.comThe Religious Orders Study is a longitudinal clinical-pathologic cohort study of aging and
Alzheimer's disease (AD). In this manuscript, we summarize the study methods including the
study design and describe the clinical evaluation, assessment of risk factors, collection of
ante-mortem biological specimens, brain autopsy and collection of selected postmortem
data. The results: 1) review the relation of neuropathologic indices to clinical diagnoses and
cognition proximate to death; 2) examine the relation of risk factors to clinical outcomes; 3) …
Alzheimer's disease (AD). In this manuscript, we summarize the study methods including the
study design and describe the clinical evaluation, assessment of risk factors, collection of
ante-mortem biological specimens, brain autopsy and collection of selected postmortem
data. The results: 1) review the relation of neuropathologic indices to clinical diagnoses and
cognition proximate to death; 2) examine the relation of risk factors to clinical outcomes; 3) …
The Religious Orders Study is a longitudinal clinical-pathologic cohort study of aging and Alzheimer’s disease (AD). In this manuscript, we summarize the study methods including the study design and describe the clinical evaluation, assessment of risk factors, collection of ante-mortem biological specimens, brain autopsy and collection of selected postmortem data. The results: 1) review the relation of neuropathologic indices to clinical diagnoses and cognition proximate to death; 2) examine the relation of risk factors to clinical outcomes; 3) examine the relation of risk factors to measures of neuropathology; and 4) summarize additional study findings. We then discuss and contextualize the study findings.
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