Catalysis of Methaemoglobin Reduction by Erythrocyte Cytochrome b5 and Cytochrome b5 Reductase

DE HULTQUIST, PG Passon - Nature New Biology, 1971 - nature.com
DE HULTQUIST, PG Passon
Nature New Biology, 1971nature.com
THE reduction of methaemoglobin is one of the few oxidation-reduction reactions known to
occur in the mature red blood cell. Approximately 3% of the circulating haemoglobin of an
adult man is oxidized each day to methaemoglobin1 and so a methaemoglobin reduction
system is needed in the cell to maintain a low concentration of methaemoglobin (normally
less than 1% of the total haemoglobin2).
Abstract
THE reduction of methaemoglobin is one of the few oxidation-reduction reactions known to occur in the mature red blood cell. Approximately 3% of the circulating haemoglobin of an adult man is oxidized each day to methaemoglobin1 and so a methaemoglobin reduction system is needed in the cell to maintain a low concentration of methaemoglobin (normally less than 1% of the total haemoglobin2).
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