MATERIALSANDMETHODS

Seven unrelated persons (mean age 63.5 ±4.2 y) participated in this study (Table 1). BMIPP scintigraphy initially revealed negative myocardial accumulation in 3 of them, so we analyzed CD36 expression on their platelets and monocytes. The remaining 4 participants were identified by blood screening for CD36 expres sion. We confirmed that all participants had a type I CD36 deficiency (neither platelets nor monocytes express CD36). Five of the 7 participants underwent coronary angiography because of their cardiac symptoms, and coronary artery disease (CAD) was diag nosed in 4 of the participants. Of the remaining 3 participants, 1 was evaluated by echocardiography as having hypertrophic cardio myopathy and 2 participants were hypertensive.