Pathogenesis of presbycusis in animal models: a review

AR Fetoni, PM Picciotti, G Paludetti, D Troiani - Experimental gerontology, 2011 - Elsevier
Presbycusis is the most common cause of hearing loss in aged subjects, reducing
individual's communicative skills. Age related hearing loss can be defined as a progressive,
bilateral, symmetrical hearing loss due to age related degeneration and it can be considered
a multifactorial complex disorder, with both environmental and genetic factors contributing to
the aetiology of the disease. The decline in hearing sensitivity caused by ageing is related to
the damage at different levels of the auditory system (central and peripheral). Histologically …