Determination of placental growth factor (PlGF) levels in healthy pregnant women without signs or symptoms of preeclampsia

C Saffer, G Olson, KA Boggess, R Beyerlein… - … An International Journal …, 2013 - Elsevier
Objective To identify a reference range for placental growth factor (PlGF) in normotensive
women without symptoms or signs of preeclampsia. Study design Comprising the study
cohort were 247 term pregnancies without preeclampsia or adverse neonatal outcomes from
16 sites in the US and Canada. Serial plasma samples were collected in 6 gestational age
(GA) intervals between 20+ 0 and 40+ 0 weeks. Non-parametric percentiles of the
distribution of PlGF were estimated in each GA interval and a parametric model was …