Evaluation of placenta growth factor and soluble Fms-like tyrosine kinase 1 receptor levels in mild and severe preeclampsia

CJ Robinson, DD Johnson, EY Chang… - American journal of …, 2006 - Elsevier
OBJECTIVE: The purpose of this study was to determine if maternal serum concentrations of
placenta growth factor (PlGF) and soluble Fms-like tyrosine kinase 1 receptor (s-Flt1) are
more abnormal in patients with severe preeclampsia compared with mild preeclampsia.
STUDY DESIGN: Serum samples were collected from 32 control patients and 80 patients
with mild or severe preeclampsia. PlGF and s-Flt1 concentrations were quantitated by
enzyme-linked immunosorbent assay (ELISA). Results are expressed as median (Q1-Q3) …