Anaerobic, glycogen-dependent transport of amino acids by the placenta
LD Longo, P Yuen, DJ Gusseck - Nature, 1973 - nature.com
LD Longo, P Yuen, DJ Gusseck
Nature, 1973•nature.comTHE concentration of amino acids is greater in foetal than in maternal blood and their
placental transport is fairly well established to depend on energy dependent processes1.
Although it is reported that placental transport of amino acids occurs only in aerobic
conditions2–4, we show here that the human placenta can accumulate amino acids
anaerobically against a concentration gradient, and that this is sustained by the utilization of
glycogen.
placental transport is fairly well established to depend on energy dependent processes1.
Although it is reported that placental transport of amino acids occurs only in aerobic
conditions2–4, we show here that the human placenta can accumulate amino acids
anaerobically against a concentration gradient, and that this is sustained by the utilization of
glycogen.
Abstract
THE concentration of amino acids is greater in foetal than in maternal blood and their placental transport is fairly well established to depend on energy dependent processes1. Although it is reported that placental transport of amino acids occurs only in aerobic conditions2–4, we show here that the human placenta can accumulate amino acids anaerobically against a concentration gradient, and that this is sustained by the utilization of glycogen.
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