Association of TMTC2 with human nonsyndromic sensorineural hearing loss

CL Runge, A Indap, Y Zhou, JW Kent… - … –Head & Neck …, 2016 - jamanetwork.com
Importance Sensorineural hearing loss (SNHL) is commonly caused by conditions that affect
cochlear structures or the auditory nerve, and the genes identified as causing SNHL to date
only explain a fraction of the overall genetic risk for this debilitating disorder. It is likely that
other genes and mutations also cause SNHL. Objective To identify a candidate gene that
causes bilateral, symmetric, progressive SNHL in a large multigeneration family of Northern
European descent. Design, Setting, and Participants In this prospective genotype and …