History, applications, and mechanisms of deep brain stimulation

S Miocinovic, S Somayajula, S Chitnis… - JAMA neurology, 2013 - jamanetwork.com
Deep brain stimulation (DBS) is an effective surgical treatment for medication-refractory
hypokinetic and hyperkinetic movement disorders, and it is being explored for a variety of
other neurological and psychiatric diseases. Deep brain stimulation has been Food and
Drug Administration–approved for essential tremor and Parkinson disease and has a
humanitarian device exemption for dystonia and obsessive-compulsive disorder.
Neurostimulation is the fruit of decades of both technical and scientific advances in the field …