Expression and localization of the Nav1. 9 sodium channel in enteric neurons and in trigeminal sensory endings: implication for intestinal reflex function and orofacial …

F Padilla, ML Couble, B Coste, F Maingret… - Molecular and Cellular …, 2007 - Elsevier
The Nav1. 9 sodium channel is expressed in nociceptive DRG neurons where it contributes
to spontaneous pain behavior after peripheral inflammation. Here, we used a newly
developed antibody to investigate the distribution of Nav1. 9 in rat and mouse trigeminal
ganglion (TG) nerve endings and in enteric nervous system (ENS). In TGs, Nav1. 9 was
expressed in the soma of small-and medium-sized, peripherin-positive neurons. Nav1. 9
was present along trigeminal afferent fibers and at terminals in lip skin and dental pulp. In …