[HTML][HTML] The potential role of podoplanin in tumour invasion
A Wicki, G Christofori - British journal of cancer, 2007 - nature.com
A Wicki, G Christofori
British journal of cancer, 2007•nature.comPodoplanin is a small mucin-like transmembrane protein, widely expressed in various
specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin-
mediated tumour invasion. We compare molecular pathways leading to single and collective
cell invasion and discuss novel distinct concepts of tumour cell invasion.
specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin-
mediated tumour invasion. We compare molecular pathways leading to single and collective
cell invasion and discuss novel distinct concepts of tumour cell invasion.
Abstract
Podoplanin is a small mucin-like transmembrane protein, widely expressed in various specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin-mediated tumour invasion. We compare molecular pathways leading to single and collective cell invasion and discuss novel distinct concepts of tumour cell invasion.
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