Flow cytometry-based assay to study HIV-1 gp120 specific antibody-dependent cellular cytotoxicity responses
J Richard, M Veillette, LA Batraville, M Coutu… - Journal of virological …, 2014 - Elsevier
Increased attention on the role of Fc-mediated effector functions against HIV-1 has led to
renewed interest into the role that antibody-dependent cellular cytotoxicity (ADCC) could
play in controlling viral transmission and/or the rate of disease progression. While 51
Chromium release assays have traditionally been used to study ADCC responses against
HIV-1, a number of alternative flow-cytometry-based assays were recently developed. In this
study, an alternative flow-cytometry-based assay was established to allow non-radioactive …
renewed interest into the role that antibody-dependent cellular cytotoxicity (ADCC) could
play in controlling viral transmission and/or the rate of disease progression. While 51
Chromium release assays have traditionally been used to study ADCC responses against
HIV-1, a number of alternative flow-cytometry-based assays were recently developed. In this
study, an alternative flow-cytometry-based assay was established to allow non-radioactive …