A new method of quaternizing amines and its use in amino acid and peptide chemistry

FCM Chen, NL Benoiton - Canadian Journal of Chemistry, 1976 - cdnsciencepub.com
FCM Chen, NL Benoiton
Canadian Journal of Chemistry, 1976cdnsciencepub.com
A new method of quaternizing amines and its use in amino acid and peptide chemistry
Page 1 A new method of quaterdzing amines and its use in amino acid and peptide
chemistry' FRANCIS CM CHEN AND N. LEO BENOITON Departmetzt of Biochemistry,
University of Ottawa, Ottawa, Canada KIN 9A9 Received July 8, 1976 FRANCIS C. M.
CHEN and N. LEO BENOITON. Can. J. Chem. 54, 3310 (1976). Methyl iodide and
potassium bicarbonate in methanol is presented as a mild, efficient, and selective reagent …
Methyl iodide and potassium bicarbonate in methanol is presented as a mild, efficient, and selective reagent for the quaternization of amino groups. It does not attack hydroxyl groups. Its use with amino acids, derivatives of lysine, and small peptides is described.
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