[HTML][HTML] The role of C4d deposition in the diagnosis of antibody-mediated rejection after lung transplantation
PR Aguilar, D Carpenter, J Ritter, RD Yusen… - American Journal of …, 2018 - Elsevier
Antibody-mediated rejection (AMR) is an increasingly recognized form of lung rejection. C4d
deposition has been an inconsistent finding in previous reports and its role in the diagnosis
has been controversial. We conducted a retrospective single-center study to characterize
cases of C4d-negative probable AMR and to compare these to cases of definite (C4d-
positive) AMR. We identified 73 cases of AMR: 28 (38%) were C4d-positive and 45 (62%)
were C4d-negative. The two groups had a similar clinical presentation, and although more …
deposition has been an inconsistent finding in previous reports and its role in the diagnosis
has been controversial. We conducted a retrospective single-center study to characterize
cases of C4d-negative probable AMR and to compare these to cases of definite (C4d-
positive) AMR. We identified 73 cases of AMR: 28 (38%) were C4d-positive and 45 (62%)
were C4d-negative. The two groups had a similar clinical presentation, and although more …