Outcomes after lung transplantation are markedly inferior to those after other solid organ
transplants. A better understanding of cellular and molecular mechanisms contributing to
lung graft injury will be critical to improve outcomes. Advances in this field have been
hampered by the lack of a mouse model of lung transplantation. Here, we report a mouse
model of vascularized aerated single lung transplantation utilizing cuff techniques. We show
that syngeneic grafts have normal histological appearance with minimal infiltration of T …