[HTML][HTML] Ets homologous factor (EHF) has critical roles in epithelial dysfunction in airway disease
The airway epithelium forms a barrier between the internal and external environments.
Epithelial dysfunction is critical in the pathology of many respiratory diseases, including
cystic fibrosis. Ets homologous factor (EHF) is a key member of the transcription factor
network that regulates gene expression in the airway epithelium in response to endogenous
and exogenous stimuli. EHF, which has altered expression in inflammatory states, maps to
the 5′ end of an intergenic region on Chr11p13 that is implicated as a modifier of cystic …
Epithelial dysfunction is critical in the pathology of many respiratory diseases, including
cystic fibrosis. Ets homologous factor (EHF) is a key member of the transcription factor
network that regulates gene expression in the airway epithelium in response to endogenous
and exogenous stimuli. EHF, which has altered expression in inflammatory states, maps to
the 5′ end of an intergenic region on Chr11p13 that is implicated as a modifier of cystic …