High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesions

Y Yamada, MH Bilsky, DM Lovelock… - International Journal of …, 2008 - Elsevier
PURPOSE: To report tumor control and toxicity for patients treated with image-guided
intensity-modulated radiotherapy (RT) for spinal metastases with high-dose single-fraction
RT. METHODS AND MATERIALS: A total of 103 consecutive spinal metastases in 93
patients without high-grade epidural spinal cord compression were treated with image-
guided intensity-modulated RT to doses of 18–24 Gy (median, 24 Gy) in a single fraction
between 2003 and 2006. The spinal cord dose was limited to a 14-Gy maximal dose. The …