Mast cell–T cell interactions
YA Mekori, DD Metcalfe - Journal of Allergy and Clinical Immunology, 1999 - Elsevier
In addition to being a major effector cell in the elicitation of allergic inflammation, mast cells
have been found to be activated in various T cell–mediated inflammatory processes and to
reside in close physical proximity to T cells. Such observations and the wide spectrum of
mediators produced and secreted by mast cells have led investigators to propose a
functional relationship between these 2 cell populations. Indeed, mast cell activation has
been reported to induce T-cell migration either directly by the release of chemotactic factors …
have been found to be activated in various T cell–mediated inflammatory processes and to
reside in close physical proximity to T cells. Such observations and the wide spectrum of
mediators produced and secreted by mast cells have led investigators to propose a
functional relationship between these 2 cell populations. Indeed, mast cell activation has
been reported to induce T-cell migration either directly by the release of chemotactic factors …