The CFSE dye dilution assay is widely used to determine the number of divisions a given
CFSE labelled cell has undergone in vitro and in vivo. In this paper, we consider how the
data obtained with the use of CFSE (CFSE data) can be used to estimate the parameters
determining cell division and death. For a homogeneous cell population (ie, a population
with the parameters for cell division and death being independent of time and the number of
divisions cells have undergone), we consider a specific biologically based “Smith–Martin” …