Nanogel engineering for new nanobiomaterials: from chaperoning engineering to biomedical applications
Y Sasaki, K Akiyoshi - The Chemical Record, 2010 - Wiley Online Library
Y Sasaki, K Akiyoshi
The Chemical Record, 2010•Wiley Online LibraryNanosize hydrogels (nanogels) are polymer nanoparticles with three‐dimensional networks,
formed by chemical and/or physical cross‐linking of polymer chains. Recently, various
nanogels have been designed, with a particular focus on biomedical applications. In this
review, we describe recent progress in the synthesis of nanogels and nanogel‐integrated
hydrogels (nanogel cross‐linked gels) for drug‐delivery systems (DDS), regenerative
medicine, and bioimaging. We also discuss chaperone‐like functions of physical cross …
formed by chemical and/or physical cross‐linking of polymer chains. Recently, various
nanogels have been designed, with a particular focus on biomedical applications. In this
review, we describe recent progress in the synthesis of nanogels and nanogel‐integrated
hydrogels (nanogel cross‐linked gels) for drug‐delivery systems (DDS), regenerative
medicine, and bioimaging. We also discuss chaperone‐like functions of physical cross …
Abstract
Nanosize hydrogels (nanogels) are polymer nanoparticles with three‐dimensional networks, formed by chemical and/or physical cross‐linking of polymer chains. Recently, various nanogels have been designed, with a particular focus on biomedical applications. In this review, we describe recent progress in the synthesis of nanogels and nanogel‐integrated hydrogels (nanogel cross‐linked gels) for drug‐delivery systems (DDS), regenerative medicine, and bioimaging. We also discuss chaperone‐like functions of physical cross‐linking nanogel (chaperoning engineering) and organic‐inorganic hybrid nanogels. © 2010 The Japan Chemical Journal Forum and Wiley Periodicals, Inc. Published online in Wiley InterScience (www.interscience.wiley.com) DOI 10.1002/tcr.201000008
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