Development of the CLASI as a tool to measure disease severity and responsiveness to therapy in cutaneous lupus erythematosus

R Klein, S Moghadam-Kia, J LoMonico… - Archives of …, 2011 - jamanetwork.com
Objective To determine how to use the Cutaneous Lupus Erythematosus Disease Area and
Severity Index (CLASI) to classify patients according to disease severity (mild, moderate,
and severe) and to identify which patients respond to therapy. Design Cohort. Setting The
connective-tissue disease clinic at the Hospital of the University of Pennsylvania,
Philadelphia. Patients Seventy-five patients with clinical or histopathologic evidence of
cutaneous lupus erythematosus or systemic lupus erythematosus were included in the …