Van Belle et al, 1 who were among the first to empha-size the potential importance of diabetes in adverse late outcomes after percutaneous coronary interventions (PCI), provide useful observations in their present study of a large cohort of diabetic patients who were treated with standard balloon angioplasty, scheduled for repeated angiography 6 months later, and followed for an average of 6.5 years. They conclude that the incidence of both nonocclusive and occlusive restenosis is higher in diabetic subjects as judged from comparison with historical control subjects. Furthermore, they report that occlusive restenosis is “a strong, independent correlate of long-term mortality.” These results implicate accelerated restenosis as both a consequence of diabetes and a cause for increased mortality after PCI in diabetic patients. They are consistent with results in prospective, long-term–mortality, controlled trials2, 3 and with results in observational mortality and angiographic studies. 4, 5