Pseudomonas aeruginosa is an important human pathogen associated with several acute
and chronic conditions, including diseases of the airways and wounds. The organism
produces pyocyanin, an extracellular redox toxin that induces oxidative stress, depletes
intracellular glutathione (GSH) and induces proliferative arrest and apoptosis, thus
compromising the ability of tissue to repair itself. GSH is an important intra-and extracellular
antioxidant, redox buffer and detoxifies xenobiotics by increasing their polarity, which …