Podocytes form the visceral layer of a kidney glomerulus and express a characteristic
octopus-like cellular architecture specialized for the ultrafiltration of blood. The cytoskeletal
dynamics and structural elasticity of podocytes rely on the self-organization of highly
interconnected actin bundles, and the maintenance of these features is important for the
intact glomerular filtration. Development of more differentiated podocytes in culture has
dramatically increased our understanding of the molecular mechanisms regulating podocyte …