Effects of n-3 fish oil on metabolic and histological parameters in NASH: a double-blind, randomized, placebo-controlled trial
CK Argo, JT Patrie, C Lackner, TD Henry… - Journal of …, 2015 - Elsevier
Background & Aims This study's aim was to assess the histological and metabolic effects of
n-3 polyunsaturated fatty acids (PUFAs) vs. placebo while adjusting for the impact of age
and weight change in NASH patients.(ClinicalTrials. gov: NCT00681408). Methods Forty-
one subjects with non-cirrhotic NASH were enrolled, and 34 completed the study. 17
received n-3 fish oil 3000 mg/day and 17 received placebo daily for 1 year with typical
counselling on caloric intake and physical activity for all subjects. Results N-3-and placebo …
n-3 polyunsaturated fatty acids (PUFAs) vs. placebo while adjusting for the impact of age
and weight change in NASH patients.(ClinicalTrials. gov: NCT00681408). Methods Forty-
one subjects with non-cirrhotic NASH were enrolled, and 34 completed the study. 17
received n-3 fish oil 3000 mg/day and 17 received placebo daily for 1 year with typical
counselling on caloric intake and physical activity for all subjects. Results N-3-and placebo …