A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order
BACKGROUND: Hay fever or seasonal allergic rhinitis (AR) is a chronic disorder associated
with IgE sensitization to grass. The underlying genetic variants have not been studied
comprehensively. There is overwhelming evidence that those who have older siblings have
less AR, although the mechanism for this remains unclear. OBJECTIVE: We sought to
identify common genetic variant associations with prevalent AR and grass sensitization
using existing genome-wide association study (GWAS) data and to determine whether …
with IgE sensitization to grass. The underlying genetic variants have not been studied
comprehensively. There is overwhelming evidence that those who have older siblings have
less AR, although the mechanism for this remains unclear. OBJECTIVE: We sought to
identify common genetic variant associations with prevalent AR and grass sensitization
using existing genome-wide association study (GWAS) data and to determine whether …