Eosinophilic esophagitis during peanut oral immunotherapy with omalizumab

CM Burk, ES Dellon, PH Steele… - The Journal of …, 2017 - jaci-inpractice.org
Oral immunotherapy (OIT) can promote desensitization to food allergens, but minimizing, or
lessening in severity, the high rate of adverse reactions is a clinical imperative. 1 The
repetitive oral administration of allergens to atopic individuals mimics exposures thought to
trigger eosinophilic esophagitis (EoE). Indeed, several cases of EoE occurring during OIT
have been noted, 2, 3 including during peanut OIT with omalizumab, a strategy intended to
reduce side effects and to allow for faster desensitization. 4 Here, we describe 2 additional …