Invasive Candida infections: evolution of a fungal pathogen

JE Edwards Jr - New England Journal of Medicine, 1991 - Mass Medical Soc
JE Edwards Jr
New England Journal of Medicine, 1991Mass Medical Soc
THE evolution of fungi of the genus candida from infrequent pathogens to among the most
common agents of nosocomial infection has been both dynamic and interesting. The story of
their emergence began in the early 1960s with events remarkably similar to those (recently
recounted in the Journal by Klein1) involving the transformation of coagulase-negative
staphylococci from a harmless commensal to an invasive pathogen. The severity of the
problem is illustrated by the data collected by the National Nosocomial Infections …
THE evolution of fungi of the genus candida from infrequent pathogens to among the most common agents of nosocomial infection has been both dynamic and interesting. The story of their emergence began in the early 1960s with events remarkably similar to those (recently recounted in the Journal by Klein1) involving the transformation of coagulase-negative staphylococci from a harmless commensal to an invasive pathogen. The severity of the problem is illustrated by the data collected by the National Nosocomial Infections Surveillance System during the past decade. Jarvis and colleagues2 reported studying 344,610 nosocomial pathogens reported to the surveillance system between . . .
The New England Journal Of Medicine