[HTML][HTML] The importance of immune dysfunction in determining outcome in acute liver failure

CG Antoniades, PA Berry, JA Wendon, D Vergani - Journal of hepatology, 2008 - Elsevier
Acute liver failure (ALF) shares striking similarities with septic shock with regard to the
features of systemic inflammation, progression to multiple organ dysfunction and functional
immunoparesis. While the existence of opposing systemic pro-and anti-inflammatory profiles
resulting in organ failure and immune dysfunction are well recognised in septic shock,
characterization of these processes in ALF has only recently been described. This review
explores the evolution of the systemic inflammation in acute liver failure, its relation to …