Through the better understanding of the genetics and clinical associations of Primary Ciliary
Dyskinesia (PCD), an autosomal recessive disorder of ciliary motility and mucociliary
clearance, the association between PCD and heterotaxic congenital heart disease (CHD)
has been established. In parallel, research into the cause of CHD has elucidated further the
role of ciliary function on the development of normal cardiovascular structure. Increased
awareness by clinicians regarding this elevated risk of PCD in patients with CHD will allow …