[HTML][HTML] An anatomically resolved mouse brain proteome reveals Parkinson disease-relevant pathways

SY Jung, JM Choi, MWC Rousseaux… - Molecular & Cellular …, 2017 - ASBMB
Here, we present a mouse brain protein atlas that covers 17 surgically distinct
neuroanatomical regions of the adult mouse brain, each less than 1 mm 3 in size. The
protein expression levels are determined for 6,500 to 7,500 gene protein products from each
region and over 12,000 gene protein products for the entire brain, documenting the
physiological repertoire of mouse brain proteins in an anatomically resolved and
comprehensive manner. We explored the utility of our spatially defined protein profiling …