Review article On the relationship between extracellular glutamate, hyperexcitation and neurodegeneration, in vivo

R Tapia, L Medina-Ceja, F Pena - Neurochemistry international, 1999 - Elsevier
In recent years there has been an increasing interest in the studies on neurodegeneration\
including the physio! logical or programmed neuronal death and the cell dis! ruption
occurring as a consequence of necrosis [This interest has been greatly stimulated by the fact
that pre! cipitate and localized neuronal destruction is a central event in the course of many
acute and chronic disorders of the central nervous system" CNS#[These disorders include
stroke" anoxia! ischemia#\hypoglycemia\cerebral trauma\epilepsy and several devastating …