Assessment of right ventricular structure and function in mouse model of pulmonary artery constriction by transthoracic echocardiography

HW Cheng, S Fisch, S Cheng, M Bauer, S Ngoy… - JoVE (Journal of …, 2014 - jove.com
Emerging clinical data support the notion that RV dysfunction is critical to the pathogenesis
of cardiovascular disease and heart failure1-3. Moreover, the RV is significantly affected in
pulmonary diseases such as pulmonary artery hypertension (PAH). In addition, the RV is
remarkably sensitive to cardiac pathologies, including left ventricular (LV) dysfunction,
valvular disease or RV infarction4. To understand the role of RV in the pathogenesis of
cardiac diseases, a reliable and noninvasive method to access the RV structurally and …