The mononuclear phagocyte system, including circulating monocytes and tissue resident
macrophages, plays an important role in acute lung injury and fibrosis. The detailed dynamic
changes of mononuclear phagocytes in the circulating, lung alveolar and interstitial
compartments in bleomycin-induced pulmonary injury model have not been fully
characterized. The present study was designed to address this issue and analyzed their
relationships with pulmonary pathological evolution after bleomycin challenge. A total of 100 …