The prognostic significance of natural killer cytotoxicity in patients with colorectal cancer

PI Tartter, B Steinberg, DM Barron… - Archives of …, 1987 - jamanetwork.com
• We evaluate the prognostic significance of preoperative natural killer (NK) cytotoxicity for
K562 cells and its relationship to other prognostic factors in 102 patients with colorectal
cancer who underwent curative resections between February 1984 and February 1985. The
18 patients who had recurrences within two years of surgery had significantly higher
numbers of preoperative peripheral blood suppressor/cytotoxic and NK cells and
significantly lower preoperative NK cytotoxicity than disease-free patients. Low preoperative …