Predictors of Outcome in Adenoid Cystic Carcinoma of Salivary Glands: A Clinicopathologic Study With Correlation Between: MYB: Fusion and Protein Expression
Adenoid cystic carcinoma (ACC) is the second most common salivary gland malignancy and
it has a high rate of recurrences and a poor long-term prognosis. Our aim was to assess the
prognostic factors in ACC and study MYB-NFIB fusion and MYB protein expression in a
large retrospective cohort of 135 patients with a median follow-up of 6.3 years. The 5-and 10-
year local recurrence-free survival (RFS) rate of 94% and 78%, 5-and 10-year distant
metastasis survival rate of 77% and 58%, and 5-and 10-year RFS of 66% and 44%. The …
it has a high rate of recurrences and a poor long-term prognosis. Our aim was to assess the
prognostic factors in ACC and study MYB-NFIB fusion and MYB protein expression in a
large retrospective cohort of 135 patients with a median follow-up of 6.3 years. The 5-and 10-
year local recurrence-free survival (RFS) rate of 94% and 78%, 5-and 10-year distant
metastasis survival rate of 77% and 58%, and 5-and 10-year RFS of 66% and 44%. The …