[HTML][HTML] Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer
N Fusco, FC Geyer, MR De Filippo, LG Martelotto… - Modern Pathology, 2016 - Elsevier
Adenoid cystic carcinoma of the breast is a rare histological type of triple-negative breast
cancer with an indolent clinical behavior, often driven by the MYB-NFIB fusion gene. Here
we sought to define the repertoire of somatic genetic alterations in two adenoid cystic
carcinomas associated with high-grade triple-negative breast cancer. The different
components of each case were subjected to copy number profiling and massively parallel
sequencing targeting all exons and selected regulatory and intronic regions of 488 genes …
cancer with an indolent clinical behavior, often driven by the MYB-NFIB fusion gene. Here
we sought to define the repertoire of somatic genetic alterations in two adenoid cystic
carcinomas associated with high-grade triple-negative breast cancer. The different
components of each case were subjected to copy number profiling and massively parallel
sequencing targeting all exons and selected regulatory and intronic regions of 488 genes …