We diagnosed prostatic adenosquamous carcinoma by prostate core needle biopsy in a 55-
year-old man with no history of prostate cancer. The prognosis, DNA analysis, and
histogenesis of this extremely rare tumor are controversial. To our knowledge, this is the first
case of adenosquamous carcinoma diagnosed by core needle biopsy in a patient with no
history of prostate cancer or hormonal therapy. We performed immunohistologic and DNA
analysis to further characterize this cancer. The clinical presentation and abnormal DNA …