[HTML][HTML] Suprabasin, a novel epidermal differentiation marker and potential cornified envelope precursor
GT Park, SE Lim, SI Jang, MI Morasso - Journal of Biological Chemistry, 2002 - ASBMB
The suprabasin gene is a novel gene expressed in mouse and human differentiating
keratinocytes. We identified a partial cDNA encoding suprabasin using a suppression
subtractive hybridization method between the proliferative basal and differentiating
suprabasal populations of the mouse epidermis. A 3′ gene-specific probe hybridized to
transcripts of 0.7-and 2.2-kb pairs on Northern blots with specific detection in differentiated
keratinocytes of stratified epithelia. The mouse gene was mapped to chromosome 7 by …
keratinocytes. We identified a partial cDNA encoding suprabasin using a suppression
subtractive hybridization method between the proliferative basal and differentiating
suprabasal populations of the mouse epidermis. A 3′ gene-specific probe hybridized to
transcripts of 0.7-and 2.2-kb pairs on Northern blots with specific detection in differentiated
keratinocytes of stratified epithelia. The mouse gene was mapped to chromosome 7 by …